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KMID : 0376119790060020051
Medical Journal of the Red Cross Hospital
1979 Volume.6 No. 2 p.51 ~ p.59
A Histopathologic Study on Vascular Changes of Myomatous Uteri

Abstract
Histopathological investigation of vascular changes in the endo and myometrium were made on 30 myomatous uteri. Sections were taken from the definite sites of the endomyometrium and/or myomatous nodules of each case for this study.
Vascular changes in the myomatous endo and myometrium were characterized by fibrous thickening of the intima, increase of collagens and elastic fibers in the media, splittitting and disruption of the internal elastic lamina and hyaline degeneration in the small arteries and arteriols proximal to the endometrium. Severity of uterine vascular changes in myometrium were more prominent than those in endometrium and/or myomatous nodules. Out of 30 myomatous uteri studied, 21 cases revealed hyaline degenerations of small arteries and arteries. Encountered in large arteries of myometrium, however, were neither finding of hyaline degeneration. It was probably attributed to the vascular fragility that might underlie the uterine bleeding as a common feature of myomatous uteri. The morphological, changes of the blood vessels were multifariously modified by aging and pregnancy, but in this study, it seems to be an apparent age related alteration in the blood vessels and the vascular changes were more marked in. the multiparous uteri as an effect of gestation and parturition may add to .the age related changes that precede.
In additions, author observed the specific feature of pericapillary hyperplasia and sclerosis of collagens, and/or fibers in endometrium, which were so called "menstrual sclerosis" in the late secretory phase and "gestation sclerosis" in the pregnant.
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